The Barki sheep is an indigenous sheep breed in Egypt that is well adapted to the harsh conditions of semi-arid regions. In this thesis, two genetic approaches, the candidate gene approach and genome-wide SNP analysis, were used to investigate the genetic basis of growth traits and milk performance in a Barki sheep population. Genetic variation has been demonstrated for these traits, which can be used to establish specific breeding programs. Understanding the genetics will provide valuable information that will help improve growth and milk performance traits in the Egyptian Barki sheep breed.<eng>