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Synthetic approaches for the synthesis of 7-azaindole derivatives using 5-amino-1R-1H-pyrrole-3-carbonitrile as useful building block ( Dissertationsschrift )

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The present work is based on the use of different synthetic methodologies using the pyrrole unit as a building block to construct new heterocyclic systems. A variety of fused and non-fused 7-azaindole derivatives were synthesized via ring opening of 3-substituted indoles and 3-nitrochromone, condensation with 4-chlorocoumarins, or using three multicomponent reactions. In addition, the azaindole backbone was subjected to typical coupling reactions.

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