Publikation: Teil einer Monographie/eines Konferenzbandes

Multi-resolution spatial simulation for molecular crowding

Grunddaten
Link
Abstract
Autoren
Einrichtung

Grunddaten

Titel	Multi-resolution spatial simulation for molecular crowding
Veröffentlicht in	Winter Simulation Conference, 2008 : WSC 2008 ; 7 - 10 Dec. 2008, Miami, FL, USA ; incorporate ... the MASM (Modeling and Analysis for Semiconductor Manufacturing) Conference , ISBN 978-1-4244-2707-9. - Piscataway, NJ : IEEE
Erscheinungsjahr	2008
Seiten (von – bis)	1384 – 1392
Jahr	2008
Publikationsform	Elektronische Ressource
Publikationsart	Teil einer Monographie/eines Konferenzbandes
Sprache	Englisch
Letzte Änderung	06.09.2018 05:03:57
Bearbeitungsstatus	durch UB Rostock abschließend validiert
Dauerhafte URL	http://purl.uni-rostock.de/fodb/pub/30923
Links zu Katalogen

Abstract

Spatial phenomena attract increasingly interest in computational biology. Molecular crowding, i.e. a dense population of macromolecules, is known to have a significant impact on the kinetics of molecules. However, an in-detail inspection of cell behavior in time and space is extremely costly. To balance between cost and accuracy, multi-resolution approaches offer one solution. Particularly, a combination of individual and lattice-population based algorithms promise an adequate treatment of phenomena like macromolecular crowding. In realizing such an approach, central questions are how to specify and synchronize the interaction between population and individual spatial level, and to decide what is best treated at a specific level, respectively. Based on an algorithm which combines the Next Subvolume Method and a simple, individual-based spatial approach, we will present possible answers to these questions, and will discuss first experimental results.

Autoren

Jeschke, Matthias
Uhrmacher, Adelinde

Externer Link

Beschreibung	Link
Link zur Online-Ressource	http://ieeexplore.ieee.org/stamp/stamp.jsp?arnumber=4736214&isnumber=4736042

Einrichtung

IEF/Bereich Informatik