Publikation: Teil einer Monographie/eines Konferenzbandes

Combining micro and macro-modeling in DEVS for computational biology

Grunddaten
Abstract
Autoren
Einrichtung

Grunddaten

Titel	Combining micro and macro-modeling in DEVS for computational biology
Veröffentlicht in	Proceedings of the 2007 Winter Simulation Conference ; [2]. - Piscataway, NJ : IEEE Service Center
Erscheinungsjahr	2007
Seiten (von – bis)	871 – 880
Jahr	2007
Publikationsform	Druckschrift
Publikationsart	Teil einer Monographie/eines Konferenzbandes
Sprache	Englisch
Letzte Änderung	17.05.2019 14:08:22
Bearbeitungsstatus	durch UB Rostock abschließend validiert
Dauerhafte URL	http://purl.uni-rostock.de/fodb/pub/30981
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Abstract

In computational biology there is an increasing need to combine micro and macro views of the system of interest. Therefore, explicit means to describe micro and macro level and the downward and upward causation that link both are required. Multi-Level-DEVS (or ml-DEVS) supports an explicit description of macro and micro level, information at macro level can be accessed from micro level and vice versa, micro models can be synchronously activated by the macro model and also the micro models can trigger the dynamics at macro level. To link both levels, different methods are combined, to those belong, value coupling, synchronous activations, variable ports, and invariants. The execution semantic of the formalism is given by an abstract simulator and its use is illustrated based on an small extract of the Wnt pathway.

Autoren

Uhrmacher, Adelinde
Ewald, Roland
John, Mathias
Maus, Carsten
Jeschke, Matthias
Biermann, Susanne

Einrichtung

IEF/Bereich Informatik