Publikation: Sonstiges

Platelet-rich plasma (PRP) as therapy for cartilage, tendon and muscle damage - German working group position statement

Grunddaten
Abstract
Autoren
Einrichtung

Grunddaten

Titel	Platelet-rich plasma (PRP) as therapy for cartilage, tendon and muscle damage - German working group position statement
Erscheinungsjahr	2020
Verlag	Springer Open
Verlagsort	Berlin; Heidelberg [u.a.]
Publikationsform	Elektronische Ressource
Publikationsart	Sonstiges
Sprache	Englisch
DOI	10.1186/s40634-020-00282-2
Letzte Änderung	11.01.2022 06:03:06
Bearbeitungsstatus	durch UB Rostock abschließend validiert
Dauerhafte URL	http://purl.uni-rostock.de/fodb/pub/67040
Links zu Katalogen

Abstract

Abstract: Purpose
Platelet rich plasma (PRP) is widely used in orthopaedics, but is still heavily debated. Therefore, a survey among the German "Working Group for Clinical Tissue Regeneration" of the German Society of Orthopaedics and Traumatology was conducted to achieve a consensus about the current therapeutical potential of PRP.

Methods
A first survey (n=65 experts, all orthopaedic/trauma surgeons) was conducted (n=13 questions). Following, a second round (n=40 experts) was conducted with 31 questions to achieve consensus in 5 categories: three most common indications, PRP application, future research areas.

Results
Therapeutic PRP application was regarded as useful (89%), possibly even more important in the future (90%). Most common indications were tendon pathologies (77%), osteoarthritis (OA) (68%), muscle injuries (57%) and cartilage damage (51%). Consensus was reached in 16/31 statements. The application of PRP for early knee OA (Kellgren-Lawrence grade II) was regarded as potentially useful, as well as for acute and chronic tendinopathies. For chronic lesions (cartilage, tendons), multiple injections (2-4) were seen preferable to singular injections. However, no sufficient data exists on the time interval between the injections. Standardization of PRP preparation, application, frequency, as well as determining the range of indication is strongly recommended.

Conclusions
There is a need of further standardization of the PRP preparation methods, indication and application protocols for knee OA and other indications, which must be further evaluated in basic science studies and randomized controlled clinical trials.

Level of evidence
Consensus of expert opinion, Level V

Autoren

Tischer, Thomas
Bode, Gerrit
Buhs, Matthias
Marquaß, Bastian
Nehrer, Stefan
Vogt, Stephan
Zinser, Wolfgang
Angele, Peter
Spahn, Gunter
Welsch, Götz Hannes
Niemeyer, Philipp
Madry, Henning

Einrichtung

UMR/Orthopädische Klinik und Poliklinik (OUK)