Publikation: Dissertationsschrift

Positive stranded RNA viruses

Grunddaten
Abstract
Autoren
Einrichtung

Grunddaten

Titel	Positive stranded RNA viruses
Untertitel	dissecting the capsid of Hepatitis E and Chikungunya viruses
Erscheinungsjahr	2010
Publikationsform	Elektronische Ressource
Publikationsart	Dissertationsschrift
Sprache	Englisch
Letzte Änderung	13.03.2013 14:32:31
Bearbeitungsstatus	durch UB Rostock abschließend validiert
Dauerhafte URL	http://purl.uni-rostock.de/fodb/pub/34989
Links zu Katalogen

Abstract

Capsid protein of two positive stranded RNA viruses, Hepatitis E virus (HEV) and Chikungunya virus (ChikV), were investigated. HEV was detected in swine serum collected in Germany. An infectious system for HEV was established and was used to check its egress. The requirement of various amino acid sequences for the autoproteolytic cleavage of ChikV capsid protease was investigated. I was also able to show that ChikV capsid is recognized by karyopherins and its export is mediated by CRM1 dependent nuclear export signal.

Autor

Thomas, Saijo

Einrichtung

MNF/Institut für Biowissenschaften (IfBI)