Publikation: Dissertationsschrift

The influence of receptor-ligand interactions on gene expression and phagosome functions in mouse macrophages

Grunddaten
Links
Abstract
Autoren
Einrichtung

Grunddaten

Titel	The influence of receptor-ligand interactions on gene expression and phagosome functions in mouse macrophages
Erscheinungsjahr	2007
Publikationsform	Elektronische Ressource
Publikationsart	Dissertationsschrift
Sprache	Englisch
Letzte Änderung	19.03.2013 10:45:27
Bearbeitungsstatus	durch UB Rostock abschließend validiert
Dauerhafte URL	http://purl.uni-rostock.de/fodb/pub/36942
Links zu Katalogen

Abstract

Phagocytosis, the cellular uptake of particles and pathogens, is an essential function of the innate immune response. In this study, latex beads conjugated to immunoglobulin G, bacterial lipopolysaccharides, mannan or avidin were used to induce the internalization via different phagocytic receptors. Analysis of uptake and maturation of phagosomes, their proteomes as well as of macrophage gene expression during phagocytosis demonstrated that receptor-ligand interactions at the cell surface trigger a specfic signaling 'signature', which contributes to the intracellular fate of phagosomes.

Autor

Hoffmann, Eik

Externe Links

Beschreibung	Link
Link zur Online-Ressource	http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2008-0050-9
Link zur Online-Ressource	http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2008-0050-9&pdf
Link zur Online-Ressource	http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2008-0050-9

Einrichtung

MNF/Institut für Biowissenschaften (IfBI)