Publikation: Dissertationsschrift

Streptamer technology allows to isolate leukemia antigen-specific CD8+ T cells

Grunddaten
Links
Abstract
Autoren
Einrichtung

Grunddaten

Titel	Streptamer technology allows to isolate leukemia antigen-specific CD8+ T cells
Erscheinungsjahr	2009
Publikationsform	Elektronische Ressource
Publikationsart	Dissertationsschrift
Sprache	Englisch
Letzte Änderung	19.03.2013 10:50:24
Bearbeitungsstatus	durch UB Rostock abschließend validiert
Dauerhafte URL	http://purl.uni-rostock.de/fodb/pub/38066
Links zu Katalogen

Abstract

In this work we investigated whether streptamer technology could purify WT1-specific CD8+ T cells, what is important for the development of adoptive immunotherapy. Sample from HLA/A2+ HDs were identified and selected by streptamer. The function of selected CD8+ T cells was identified by the staining of phenotypic markers. The results showed that streptamer permits the detection and selection of WT1-specific CD8+ T cells in the PBMCs from HDs. The naïve function of selected CD8+ T cells was preserved and most selected CD8+ T cells demonstrated an effector T cell immunophenotype.

Autor

Wang, Xinchao

Externe Links

Beschreibung	Link
Metadaten	http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2009-0196-0
Volltext (kostenfrei zugänglich ohne Registrierung)	http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2009-0196-0&pdf
Link zur Online-Ressource	http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2009-0196-0
Link zur Online-Ressource	http://rosdok.uni-rostock.de/file/rosdok_derivate_000000004099/Dissertation_Wang_2009.pdf
Link zur Online-Ressource	http://d-nb.info/99976232X/34

Einrichtung

UMR/Zentrum für Innere Medizin (ZIM)