Publikation: Dissertationsschrift

Spatio-temporal control of Wnt/-catenin signaling during fate commitment of human neural progenitor cells

Grunddaten
Abstract
Autoren
Einrichtung

Grunddaten

Titel	Spatio-temporal control of Wnt/-catenin signaling during fate commitment of human neural progenitor cells
Erscheinungsjahr	2010
Publikationsform	Elektronische Ressource
Publikationsart	Dissertationsschrift
Sprache	Englisch
Letzte Änderung	19.12.2020 06:04:46
Bearbeitungsstatus	durch UB Rostock abschließend validiert
Dauerhafte URL	http://purl.uni-rostock.de/fodb/pub/39034
Links zu Katalogen

Abstract

The Wnt/beta-catenin pathway is involved in neural stem cell self-renewal and neuronal differentiation. Further understanding of these processes is a prerequisite of cell replacement therapies in neurodegenerative diseases such as Parkinson's disease. In this context, the role of Wnt/beta-catenin signaling was studied in this thesis which substantiates the presently limited knowledge about neurogenesis in human cell models and shows parallels between the mechanistic knowledge based on rodent models and the use of human neural stem cells for cell replacement strategies in neurodegenerative diseases.

Autor

Bader, Benjamin

Einrichtung

MNF/Institut für Biowissenschaften (IfBI)