Publikation: Dissertationsschrift

Patient-individual models of gliomas

Grunddaten
Links
Abstract
Autoren
Einrichtung

Grunddaten

Titel	Patient-individual models of gliomas
Untertitel	establishment, characterization and applications
Erscheinungsjahr	2013
Publikationsform	Elektronische Ressource
Publikationsart	Dissertationsschrift
Sprache	Englisch
Letzte Änderung	29.10.2013 17:03:11
Bearbeitungsstatus	durch UB Rostock abschließend validiert
Dauerhafte URL	http://purl.uni-rostock.de/fodb/pub/42745
Links zu Katalogen

Abstract

Glioblastomas are the most common and aggressive brain tumors. The aim was establishing tumor models from individual patients (in vitro and in vivo). Modeling was successful from fresh and of note also from vitally frozen patient tumors. The models were characterized in direct comparison to the original tumors. Molecular features as mutations, amplifications and epigenetic alterations were highly maintained. Extensive drug sensitivity screens were performed. These well-defined patient individual models are ideal for establishment of individualized therapies and even immunological strategies.

Autor

Linnebacher, Christina Susanne

Externe Links

Beschreibung	Link
Metadaten	http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2013-0132-4
Volltext (kostenfrei zugänglich ohne Registrierung)	http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2013-0132-4&pdf
Link zur Online-Ressource	http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2013-0132-4

Einrichtung

MNF/Institut für Biowissenschaften (IfBI)