Publikation: Dissertationsschrift

Identification of host cellular requirements for positive strand RNA viruses

Grunddaten
Links
Abstract
Autoren
Einrichtung

Grunddaten

Titel	Identification of host cellular requirements for positive strand RNA viruses
Untertitel	Hepatitis C virus and hepatits E virus
Erscheinungsjahr	2011
Publikationsform	Elektronische Ressource
Publikationsart	Dissertationsschrift
Sprache	Englisch
Letzte Änderung	30.11.2013 02:12:38
Bearbeitungsstatus	durch UB Rostock abschließend validiert
Dauerhafte URL	http://purl.uni-rostock.de/fodb/pub/43081
Links zu Katalogen

Abstract

Investigation of the host cellular requirements of two positive strand RNA viruses, by microarray, phospho-proteome array and by siRNA screening identified differential expression of host genes during hepatitis C virus viral entry. Also my studies suggest that NS4B regulates a newly identified oncogenic pathway. For hepatitis E virus, I looked for the cellular effects conferred by the capsid protein ORF2, and the results showed that ORF2 induced activation of CHOP did not lead to apoptosis which might be due to the up regulation of anti-apoptotic chaperones like Hsp72.

Autor

John, Lijo

Externe Links

Beschreibung	Link
Metadaten	http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2013-0159-8
Volltext (kostenfrei zugänglich ohne Registrierung)	http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2013-0159-8&pdf
Link zur Online-Ressource	http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2013-0159-8

Einrichtung

MNF/Institut für Biowissenschaften (IfBI)