Publikation: Dissertationsschrift

Improved synthesis of 2,3-diacetamidouronates which are present in bacterial envelope

Grunddaten
Abstract
Autoren

Grunddaten

Titel	Improved synthesis of 2,3-diacetamidouronates which are present in bacterial envelope
Erscheinungsjahr	2013
Publikationsform	Elektronische Ressource
Publikationsart	Dissertationsschrift
Sprache	Englisch
Letzte Änderung	21.01.2014 16:13:57
Bearbeitungsstatus	durch UB Rostock abschließend validiert
Dauerhafte URL	http://purl.uni-rostock.de/fodb/pub/43459
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Abstract

Diacetamidodideoxyuronic acids are components of lipopolysaccarides present in bacterial cell wall. There are very few publications reporting the preparation of this class of sugars. Hence, we present the synthesis of gluco-, galacto- and manno- configured sugars of 2,3-diacetamido-2,3-dideoxy-D-uronates. These monosaccharaides can be employed as glycosyl donors and acceptors in glycosylation reactions to produce larger glycosylates which can serve as components of antibiotics. Currently, the target molecules were synthesized in high yields with good reproducibility and scalability.

Autor

Jegannathan, Jaya Shanmuga Prakash