Publikation: Dissertationsschrift

A systems biology approach to unravel the cellular function of microRNAs

Grunddaten
Links
Abstract
Autoren
Einrichtung

Grunddaten

Titel	A systems biology approach to unravel the cellular function of microRNAs
Erscheinungsjahr	2012
Publikationsform	Elektronische Ressource
Publikationsart	Dissertationsschrift
Sprache	Englisch
Letzte Änderung	25.04.2014 12:51:28
Bearbeitungsstatus	durch UB Rostock abschließend validiert
Dauerhafte URL	http://purl.uni-rostock.de/fodb/pub/44629
Links zu Katalogen

Abstract

The systems biology approach, combining biological data with mathematical modelling, provides the means to elucidate the role of miRNAs in signalling pathways and gene regulatory networks. The approach is characterised by a cyclic process, including biological network construction, mathematical modelling, simulation and experimental validation. Using this approach, I first investigate the regulatory role of miR-34a in a signalling pathway. Second, the investigation of the regulation of a miRNA target hub by multiple and cooperative miRNAs is presented.

Autor

Lai, Xin

Externe Links

Beschreibung	Link
Metadaten	http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2014-0077-5
Volltext (kostenfrei zugänglich ohne Registrierung)	http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2014-0077-5&pdf
Link zur Online-Ressource	http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2014-0077-5

Einrichtung

IEF/Bereich Informatik