Publikation: Dissertationsschrift

MicroRNA and messengerRNA expression changes during interferon-beta and glatiramer acetate treatment in peripheral blood cells of multiple sclerosis patients

Grunddaten
Abstract
Autoren
Einrichtung

Grunddaten

Titel	MicroRNA and messengerRNA expression changes during interferon-beta and glatiramer acetate treatment in peripheral blood cells of multiple sclerosis patients
Erscheinungsjahr	2014
Publikationsform	Elektronische Ressource
Publikationsart	Dissertationsschrift
Sprache	Englisch
Letzte Änderung	16.06.2015 02:14:01
Bearbeitungsstatus	durch UB Rostock abschließend validiert
Dauerhafte URL	http://purl.uni-rostock.de/fodb/pub/48362
Links zu Katalogen

Abstract

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system. There are many types of disease-modifying drugs available but none of them can cure MS. The studies reported in this thesis analyzed the changes which happen at the transcriptome level during the course of treatment with glatiramer acetate (GA) and interferon-beta-1b. The studies reported revealed several differentially expressed transcripts which included both mRNAs and microRNAs. These can be considered as biomarkers for therapy monitoring and help to better understand the mechanisms of action of the drugs.

Autor

Thamilarasan, Madhan

Einrichtung

UMR/Klinik und Poliklinik für Neurologie (KN)