Publikation: Dissertationsschrift

Functionalization of 2-nitroindole and (+)-estrone via palladium-catalyzed cross-coupling reactions

Grunddaten
Abstract
Autoren
Einrichtung

Grunddaten

Titel	Functionalization of 2-nitroindole and (+)-estrone via palladium-catalyzed cross-coupling reactions
Erscheinungsjahr	2015
Verlag	Universität Rostock
Verlagsort	Rostock
Publikationsform	Elektronische Ressource
Publikationsart	Dissertationsschrift
Sprache	Englisch
Letzte Änderung	28.03.2017 16:18:51
Bearbeitungsstatus	durch UB Rostock abschließend validiert
Dauerhafte URL	http://purl.uni-rostock.de/fodb/pub/52264
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Abstract

Functionalization of naturally occurring frameworks via palladium-catalyzed cross-coupling reactions was studied. This includes arylation of indoles via CH-activation reaction, alkynylation of (+)-estrone via Sonogashira reaction and arylation of (+)-estrone via Suzuki-Miyaura reaction. The methods were optimized, series of new substances were synthesized and the scope and limitations of the reactions were studied. Certain products showed significant activity as alkaline phosphatases inhibitors.

Autor

Ivanov, Anton

Einrichtung

MNF/Institut für Chemie (IfCh)