Publikation: Dissertationsschrift

Magnetic nanoparticle-based gene delivery

Grunddaten
Link
Abstract
Autoren
Einrichtung

Grunddaten

Titel	Magnetic nanoparticle-based gene delivery
Untertitel	mechanisms and clinical perspectives
Erscheinungsjahr	2016
Verlag	Universität Rostock
Verlagsort	Rostock
Publikationsform	Elektronische Ressource
Publikationsart	Dissertationsschrift
Sprache	Englisch
Letzte Änderung	29.03.2017 05:04:29
Bearbeitungsstatus	durch UB Rostock abschließend validiert
Dauerhafte URL	http://purl.uni-rostock.de/fodb/pub/54474
Links zu Katalogen

Abstract

The development of safe and efficient gene delivery systems is the key to the overall success of gene therapy. This work introduced a MNP-based nonviral gene delivery approach for transfection in clinically relevant cells. Moreover, the in vitro mechanism studies could explained the beneficial properties of the proposed carrier design. This work demonstrated, that proposed system could efficiently and safely transfect human bone marrow derived mesenchymal stem cells. Additionaly, the clinical perspectives of MNP-based gene therapy were discussed and evaluated in this dissertation.

Autor

Delyagina, Evgenya

Externer Link

Beschreibung	Link
Link zur Online-Ressource (kostenfrei zugänglich ohne Registrierung)	http://rosdok.uni-rostock.de/resolve/urn/urn:nbn:de:gbv:28-diss2017-0038-4

Einrichtung

UMR/Klinik und Poliklinik für Herzchirurgie