Publikation: Dissertationsschrift

Potential intermediates for antiviral and antitumor agents

Grunddaten
Abstract
Autoren

Grunddaten

Titel	Potential intermediates for antiviral and antitumor agents
Erscheinungsjahr	2018
Verlag	Universität Rostock
Verlagsort	Rostock
Publikationsform	Elektronische Ressource
Publikationsart	Dissertationsschrift
Sprache	Englisch
DOI	10.18453/rosdok_id00002278
Letzte Änderung	31.07.2018 05:03:55
Bearbeitungsstatus	durch UB Rostock abschließend validiert
Dauerhafte URL	http://purl.uni-rostock.de/fodb/pub/57288
Links zu Katalogen

Abstract

In this work, potential intermediates for antiviral and antitumor agents were successfully synthesized. This thesis is focused on the development of the 2-deoxy-D-ribofuranose analogues, due to the similarity with DNA building blocks, with diamine moieties that should be able to form metal complexes similar to cisplatin. This thesis deals with the synthesis and characterization of C-nucleoside analogues of D-ribose. In addition, we have succeeded in obtaining several 2-deoxy-D-ribofuranose derivatives with ethylenediamine group on a spacer with one or three carbon atoms to the sugar moiety.

Autor

Apelt, Helena