Publikation: Dissertationsschrift

Proteome profiling of maternal serum

Grunddaten
Abstract
Autoren

Grunddaten

Titel	Proteome profiling of maternal serum
Untertitel	a novel approach for intrauterine growth restriction screening during pregnancy
Erscheinungsjahr	2020
Verlag	Universität Rostock
Verlagsort	Rostock
Publikationsform	Elektronische Ressource
Publikationsart	Dissertationsschrift
Sprache	Englisch
DOI	10.18453/rosdok_id00002801
Letzte Änderung	17.11.2020 06:06:05
Bearbeitungsstatus	durch UB Rostock abschließend validiert
Dauerhafte URL	http://purl.uni-rostock.de/fodb/pub/64436
Links zu Katalogen

Abstract

Fetal growth restriction affects pregnancies leading to perinatal mortality and morbidity. Current diagnostic method is by ultrasound inspection but cannot differentiate SGA fetuses from IUGR fetuses. Maternal serum from IUGR, SGA and control pregnant women were analysed using affinity-mass spectrometry. Separation confidence reached a sensitivity of 0.90, specificity of 0.79 with an area under curve of 0.88 in receiver operator characteristics. Proteome profiling by affinity-mass spectrometry during pregnancy provides a reliable method for risk assessment of impaired development in fetuses.

Autor

Okai, Charles Ayensu