Publikation: Dissertationsschrift

Optimisation of stem cell based approaches towards cardiac regeneration

Grunddaten
Abstract
Autoren

Grunddaten

Titel	Optimisation of stem cell based approaches towards cardiac regeneration
Erscheinungsjahr	2019
Verlag	Universität Rostock
Verlagsort	Rostock
Publikationsform	Elektronische Ressource
Publikationsart	Dissertationsschrift
Sprache	Englisch
DOI	10.18453/rosdok_id00002896
Letzte Änderung	29.01.2021 06:05:20
Bearbeitungsstatus	durch UB Rostock abschließend validiert
Dauerhafte URL	http://purl.uni-rostock.de/fodb/pub/64937
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Abstract

Aberrant behaviour of resident cells causes several illnesses. Among them, cardiovascular diseases are the leading cause of death in the western world. The human heart possesses only negligible myocardial regeneration capacity after a myocardial infarction, thus, it cannot compensate the massive cell loss self-reliantly. The thesis addresses the optimization of different cell biological approaches for enrichment of cardiac subtypes. Moreover, the thesis demonstrates different genetic manipulation strategies (DNA-, mRNA- and microRNA-based) for an efficient modulation of cell fate.

Autor

Thiele, Frauke