Publikation: Dissertationsschrift

Defining the role of human endogenous retroviruses in pluripotency of colorectal cancer cells

Grunddaten
Abstract
Autoren
Einrichtung

Grunddaten

Titel	Defining the role of human endogenous retroviruses in pluripotency of colorectal cancer cells
Erscheinungsjahr	2021
Verlagsort	Rostock
Publikationsform	Druckschrift
Publikationsart	Dissertationsschrift
Sprache	Englisch
Letzte Änderung	11.11.2022 06:01:50
Bearbeitungsstatus	durch UB Rostock abschließend validiert
Dauerhafte URL	http://purl.uni-rostock.de/fodb/pub/68761
Links zu Katalogen

Abstract

The mortality rate in colorectal cancer patients is still high. One of the main consequences of treatment failure is tumor relapse. It is presumed that cancer stem cells (CSCs) are the cause of cancer recurrence and metastasis due to their cellular plasticity. These cells are capable to evade the immune system and endure nutritional deprivation, resulting in CSCs survival after treatment and restoring tumor growth after cancer cell elimination. Thus, precise characterization, successful targeting, and eradication of CSCs can improve cancer treatment.

Autor

Shokraie, Fatemeh

Einrichtung

UMR/Rudolf-Zenker-Institut für Experimentelle Chirurgie