Publikation: Dissertationsschrift

Stochastic modelling of subcellular biochemical systems

Grunddaten
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Abstract
Autoren
Einrichtung

Grunddaten

Titel	Stochastic modelling of subcellular biochemical systems
Erscheinungsjahr	2009
Publikationsform	Elektronische Ressource
Publikationsart	Dissertationsschrift
Sprache	Englisch
Letzte Änderung	19.03.2013 10:48:55
Bearbeitungsstatus	durch UB Rostock abschließend validiert
Dauerhafte URL	http://purl.uni-rostock.de/fodb/pub/31381
Links zu Katalogen

Abstract

Stochastic approaches are needed for modelling many cellular processes to capture noise effects. The difficulty of solving the chemical master equation, the most common formulation of stochastic models, is circumvented by stochastic simulations and analytical approximations. The central theme here is one such approximation, the two-moment approximation (2MA) which represents the mean-covariance coupling. Our 2MA formulation allows non-elementary reactions and relative concentrations. The approach is applied to the fission yeast cell cycle model. The analytical model reproduces the relevant experimental data.

Autor

Ullah, Mukhtar

Externe Links

Beschreibung	Link
Metadaten	http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2009-0128-8
Volltext (kostenfrei zugänglich ohne Registrierung)	http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2009-0128-8&pdf
Link zur Online-Ressource	http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2009-0128-8

Einrichtung

IEF/Bereich Informatik