Publikation: Dissertationsschrift

In vitro and in vivo characterization of neural progenitor cells as putative candidates for experimental studies and clinical trials in cell replacement therapy for neurodegenerative diseases

Grunddaten
Links
Abstract
Autoren
Einrichtung

Grunddaten

Titel	In vitro and in vivo characterization of neural progenitor cells as putative candidates for experimental studies and clinical trials in cell replacement therapy for neurodegenerative diseases
Erscheinungsjahr	2008
Publikationsform	Elektronische Ressource
Publikationsart	Dissertationsschrift
Sprache	Englisch
Letzte Änderung	19.03.2013 10:49:08
Bearbeitungsstatus	durch UB Rostock abschließend validiert
Dauerhafte URL	http://purl.uni-rostock.de/fodb/pub/31478
Links zu Katalogen

Abstract

Fetal conditionally immortalized striatal cells ST14A and human mesencephalic neural progenitor cells (NPCs) were studied with respect to proliferation and differentiation in in vitro experiments. In in vivo experiments, human NPCs were investigated after transplantation into neonatal and adult hemiparkinsonian rat striatum. The survival, migration and dopaminergic (DAergic) differentiation of human NPCs in the host brain was investigated. Improvement in lesion-induced motor impairment has been demonstrated in both groups of hemiparkinsonian rats, independently from DA-ergic differentiation.

Autor

Hovakimyan, Marina

Externe Links

Beschreibung	Link
Metadaten	http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2009-0119-0
Volltext (kostenfrei zugänglich ohne Registrierung)	http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2009-0119-0&pdf
Link zur Online-Ressource	http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2009-0119-0

Einrichtung

Universitätsmedizin Rostock (UMR)