Publikation: Dissertationsschrift

KCNQ channel opening as a powerful mechanism for vasodilation

Grunddaten
Links
Abstract
Autoren
Einrichtung

Grunddaten

Titel	KCNQ channel opening as a powerful mechanism for vasodilation
Erscheinungsjahr	2011
Publikationsform	Elektronische Ressource
Publikationsart	Dissertationsschrift
Sprache	Englisch
Letzte Änderung	13.03.2013 14:34:48
Bearbeitungsstatus	durch UB Rostock abschließend validiert
Dauerhafte URL	http://purl.uni-rostock.de/fodb/pub/40960
Links zu Katalogen

Abstract

KCNQ channels were recently found in the vascular system. We have tested the hypothesis that KCNQ channels are powerful targets for relaxation of small systemic and pulmonary arteries. In rat Gracilis arteries we found mRNA expression for KCNQ1, KCNQ3, KCNQ4 and KCNQ5 channels. We found that KCNQ channels mediate vessel relaxation induced by experimental modulators in systemic and pulmonary circulation, in normo- and hypertensive model. Conclusion: KCNQ channels could be powerful targets for vessel relaxation, also in pathological hypertensive conditions.

Autor

Zhuravleva, Nadezda

Externe Links

Beschreibung	Link
Metadaten	http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2012-0095-9
Volltext (kostenfrei zugänglich ohne Registrierung)	http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2012-0095-9&pdf
Link zur Online-Ressource	http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2012-0095-9

Einrichtung

UMR/Oscar-Langendorff-Institut für Physiologie