Publikation: Dissertationsschrift

Expression of and immune responses to leukemia antigens in patients with hematological malignancies

Grunddaten
Links
Abstract
Autoren
Einrichtung

Grunddaten

Titel	Expression of and immune responses to leukemia antigens in patients with hematological malignancies
Erscheinungsjahr	2011
Publikationsform	Elektronische Ressource
Publikationsart	Dissertationsschrift
Sprache	Englisch
Letzte Änderung	30.11.2013 02:12:38
Bearbeitungsstatus	durch UB Rostock abschließend validiert
Dauerhafte URL	http://purl.uni-rostock.de/fodb/pub/43079
Links zu Katalogen

Abstract

Leukemia cells are characterized by differentially expressed leukemia-associated antigens (LAAs). We wondered whether the expression of the LAAs WT1 and RHAMM as well as the T cellular immune response to these LAAs correlated with the clinical outcome of patients suffering from leukemia. We investigated the expression of WT1 and RHAMM at RNA level using qPCR before and after treatment. We concluded that WT1 is a suitable marker for MRD after allogeneic SCT and that a WT1-specific T cell response might contribute to the maintenance of CR.

Autor

Casalegno Garduño, Rosaely

Externe Links

Beschreibung	Link
Metadaten	http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2013-0153-1
Volltext (kostenfrei zugänglich ohne Registrierung)	http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2013-0153-1&pdf
Link zur Online-Ressource	http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2013-0153-1

Einrichtung

MNF/Institut für Biowissenschaften (IfBI)